Soru
\nBende kans\u0131zl\u0131k tespit edildi. Demir tedavisine yan\u0131t al\u0131namay\u0131nca doktorlar Akdeniz anemisinden \u015f\u00fcphelendiler. Bunun te\u015fhisi nas\u0131l yap\u0131l\u0131r? Te\u015fhis Akdeniz anemisi gelirse tedavide ne yapmak gerekir?<\/p>\n
Yan\u0131t
\nAkdeniz y\u00f6resinde s\u0131k g\u00f6r\u00fclen beta talasemi ta\u015f\u0131y\u0131c\u0131l\u0131\u011f\u0131 genellikle Akdeniz anemisi olarak bilinmektedir. \u00dclkemizde ve \u00f6zellikle K\u0131br\u0131s\u2019ta nadir olmayarak g\u00f6r\u00fclmektedir. Bu durum do\u011fumla birlikte ortaya \u00e7\u0131kan kal\u0131tsal bir bozukluktur. En \u00f6nemli bulgusu kans\u0131zl\u0131kt\u0131r. Kans\u0131zl\u0131\u011f\u0131n nedeni alyuvarlar\u0131n \u00f6m\u00fcrlerinin normale g\u00f6re daha k\u0131sa olmas\u0131d\u0131r. Ta\u015f\u0131y\u0131c\u0131larda kans\u0131zl\u0131k \u00e7ok a\u011f\u0131r de\u011fildir ve do\u011fumdan itibaren g\u00f6r\u00fcld\u00fc\u011f\u00fc i\u00e7in ki\u015fi bu duruma al\u0131\u015fm\u0131\u015ft\u0131r. Talasemi ta\u015f\u0131y\u0131c\u0131l\u0131\u011f\u0131 demir eksikli\u011fi kans\u0131zl\u0131\u011f\u0131yla kar\u0131\u015fabilir. Kans\u0131zl\u0131\u011f\u0131 olan ki\u015filer yeterince tetkik edilmezlerse yanl\u0131\u015fl\u0131kla demir eksikli\u011fi gibi kabul edilip gereksiz yere demir al\u0131rlar. Oysa basit kan testleri olan \u2018periferik kan yaymas\u0131\u2019 ve \u2018hemoglobin elektroferezi\u2019 yapmak suretiyle hastal\u0131\u011fa tan\u0131 koymak m\u00fcmk\u00fcnd\u00fcr. <\/p>\n
Talasemide h\u0131zl\u0131 y\u0131k\u0131lan alyuvarlar\u0131 yerine koymak i\u00e7in kemik ili\u011fi daha \u00e7ok \u00e7al\u0131\u015fmak zorundad\u0131r. Bu da alyuvar yap\u0131m\u0131nda rol oynayan bir B vitamini olan folik asit\u2019e olan ihtiyac\u0131 art\u0131r\u0131r. Dolay\u0131s\u0131yla ta\u015f\u0131y\u0131c\u0131lar\u0131n zaman zaman kanda folik asit d\u00fczeylerine bakt\u0131rmas\u0131, ihtiya\u00e7 durumunda a\u011f\u0131zdan al\u0131nan bu vitamini kullanmas\u0131 gerekir. Bu hastalarda gebelik gibi kans\u0131zl\u0131\u011f\u0131n a\u011f\u0131rla\u015ft\u0131\u011f\u0131 durumlarda buna ba\u011fl\u0131 semptomlar ortaya \u00e7\u0131kabilir. Kalp \u00e7arp\u0131nt\u0131s\u0131, halsizlik olu\u015fabilir. O takdirde kan transf\u00fczyonu yapmak gerekir. Ta\u015f\u0131y\u0131c\u0131lardaki kans\u0131zl\u0131k hafif oldu\u011fu i\u00e7in tedavide genellikle bunlar\u0131n d\u0131\u015f\u0131nda fazla bir \u015fey yapmaya gerek yoktur. Burada \u00f6nemli olan \u00e7ocuklara ta\u015f\u0131y\u0131c\u0131l\u0131\u011f\u0131n ge\u00e7ip ge\u00e7medi\u011finin tespit edilmesidir. E\u015flerden birinde talasemi ta\u015f\u0131y\u0131c\u0131l\u0131\u011f\u0131 varsa \u00e7ocuklarda ta\u015f\u0131y\u0131c\u0131l\u0131k olas\u0131l\u0131\u011f\u0131 % 50\u2019ye yakla\u015f\u0131r. Nadir g\u00f6r\u00fclen bir durum olmakla birlikte her iki e\u015fte de ta\u015f\u0131y\u0131c\u0131l\u0131k tespit edilirse \u00e7ocuklar\u0131n d\u00f6rtte birinde a\u011f\u0131r talasemi hastal\u0131\u011f\u0131 olabilir. Bu durum ta\u015f\u0131y\u0131c\u0131l\u0131ktan \u00e7ok farkl\u0131, \u00f6l\u00fcmle sonu\u00e7lanabilen bir hastal\u0131kt\u0131r. Bu nedenle \u00e7ocuk yapmak isteyen \u00e7iftlerin mutlaka kan testi yapt\u0131rarak kendilerini talasemi ta\u015f\u0131y\u0131c\u0131l\u0131\u011f\u0131 y\u00f6n\u00fcnden tetkik ettirmesinde yarar vard\u0131r. G\u00fcn\u00fcm\u00fczde gebe bir annenin \u00e7ocu\u011funda a\u011f\u0131r talasemi hastal\u0131\u011f\u0131 \u015f\u00fcphesi varsa gebelik s\u0131ras\u0131nda \u00e7ocuktan DNA \u00f6rne\u011fi al\u0131nabilmekte ve \u00e7ocu\u011fun hasta olup olmayaca\u011f\u0131 tespit edilebilmektedir. <\/p>\n","protected":false},"excerpt":{"rendered":"
Soru Bende kans\u0131zl\u0131k tespit edildi. Demir tedavisine yan\u0131t al\u0131namay\u0131nca doktorlar Akdeniz anemisinden \u015f\u00fcphelendiler. Bunun te\u015fhisi nas\u0131l yap\u0131l\u0131r? Te\u015fhis Akdeniz anemisi gelirse tedavide ne yapmak gerekir? Yan\u0131t Akdeniz y\u00f6resinde s\u0131k g\u00f6r\u00fclen beta talasemi ta\u015f\u0131y\u0131c\u0131l\u0131\u011f\u0131 genellikle Akdeniz anemisi olarak bilinmektedir. \u00dclkemizde ve \u00f6zellikle K\u0131br\u0131s\u2019ta nadir olmayarak g\u00f6r\u00fclmektedir. Bu durum do\u011fumla birlikte ortaya \u2026<\/p>\n